BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250701T184241EDT-6624d6h1jM@132.216.98.100 DTSTAMP:20250701T224241Z DESCRIPTION:James Hanley\, PhD\n\nEmeritus Professor\n Department of Epidemi ology\, Biostatistics and Occupational Health |\n Ðãɫֱ²¥\n\nWHEN : Wednesday\, November 27\, 2024\, from 3:30 to 4:30 p.m.\n WHERE: Hybrid | 2001 Ðãɫֱ²¥ College Avenue\, Room 1201\; Zoom\n NOTE: James Hanley will be presenting in-person\n\nAbstract\n\nIn epidemiological research\, the ind ividually-matched (and possibly nested) case-control study and conditional logistic regression are often thought of together (see their Wikipedia en tries). Statisticians and epidemiologists generally cite the publications by Prentice & Breslow and by Breslow et al. in 1978 as the first descripti on and use of conditional logistic regression\, while economists cite the 1973 book chapter (on consumer choices) by Nobel laureate McFadden. I rece ntly described the until-now-unrecognized use of\, and way of fitting\, th is model in 1934 by Lionel Penrose and Ronald Fisher.\n\nIn this talk\, I will first describe ways in which conditional logistic regression is used today. I will then go back to earlier versions of the case-control study\, and the gradual refinements that gave it the respectability it has today. I will show that\, through their strategic sampling of the Quebec cohort of asbestos workers\, and (more recently) of large administrative and clin ical databases\, Ðãɫֱ²¥ epidemiologists and biostatisticians played a very large role in its coming of age. They also connected it with a major deve lopment in survival analysis. The BMJ still insists on using subtitles (‘a cohort study’\; ‘a case-control study’) to separate and implicitly rank t hese study designs. I will argue that we should no longer view them as sep arate entities\, but as minor variations on a singular study design: THE ‘ etiologic study.’\n\nThe talk will be non-technical\, and is aimed at all who are interested in etiological research.\n\n* See: Biometrika\, https:/ /doi.org/10.1093/biomet/asae038\n Published: 08 August 2024\, or here: http s://jhanley.biostat.mcgill.ca/Reprints\n\n \n\nSpeaker bio\n\nJames Hanley \, an emeritus professor\, spend his first 7 working years as a biostatist ician in clinical trials in cancer\, and then 43 years at Ðãɫֱ²¥\, startin g out in a department of Epidemiology and Health (later to become Epidemio logy and Biostatistics\, before being given its current name). He continue s to take an interest in ways of teaching statistics\, and in the history of public health\, epidemiology\, and statistics. For more information\, p lease visit: https://jhanley.biostat.mcgill.ca\n\n \n DTSTART:20241127T203000Z DTEND:20241127T213000Z SUMMARY:The first ‘nested case-control’ study and the first conditional log istic regression URL:/epi-biostat-occh/channels/event/first-nested-case -control-study-and-first-conditional-logistic-regression-360434 END:VEVENT END:VCALENDAR